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LOST CELLS - Exodus of biological stem cell units Cryo-save across Eastern Europe

An investigative series 'LOST CELLS' (podcasts and RTS television film to follow) examined the 'cryo-save' scandal and its repercussions across Europe: https://www.swissinfo.ch/eng/lostcells/

It would be excellent if this could contribute to the exposure of the sinister intentions of the people and companies in question in the course of these investigations and inquiries.

But it should certainly not be an indiscriminate act of mistrust towards all those who strive to do a good job in the magnificent and very important activity of processing and storing stem cells from neonatal tissue (*).

First of all, a reminder of the facts of the so nauseating 'Cryo-save' affair:

In the spring of 2019, after holding out the prospect of rescuing its company, which was then in great difficulty, to the main shareholder of Cryo-save AG for many months, the Polish group FAMICORD-PBKM withdrew from any takeover but managed to take back to Poland, without financial compensation, total operational control of 55 huge nitrogen containers nitrogen (called tanks) filled with samples from Cryo-Save customers.
Cryo-Save was then, and had been for two decades, Europe's undisputed number one in the private stem cell sector, with almost 400,000 customers throughout Europe and far beyond. This source of precious cells was an equally gigantic and tempting "prey" for the European number 2 (just behind Cryo-Save), which at the time was FAMICORD-PBKM.

At almost the same time, in the summer of 2019, and therefore before Cryo-save went bankrupt, the American-Emirati (Los Angeles-Dubai) group CSG.BIO had also apparently acquired various rights from Cryo-save and its main shareholder over the same tanks and their contents, including the related data.
Therefore, from 2020, and after these two parties had tried in vain to divide up among themselves the giant prey that constituted the cells of these hundreds of thousands of parents, CSG.BIO went to trial with FAMICORD-PBKM with the aim of recovering what it also coveted with great greed.

Since then, and on the backs of these hundreds of thousands of parents taken hostage, there have been endless legal disputes between FAMICORD-PBKM and CSG.BIO.

However, a 56th tank was left standing, which had escaped this massive biological exodus led by FAMICORD-PBKM in just a few hours, mainly due to the haste of the transport to Poland.

But this tank contained almost 4,000 samples from Swiss children!
And it was in Holland at the time?!

In fact, the biological content of this 56th tank was indeed threatened with irretrievable loss, as there was no authorised stem cell biobank to really take care of it, and CSG. BIO, which had de facto taken over control from LindeGas in Holland, had absolutely no authorisation in Europe, no laboratory and not even any staff, even though these are absolutely essential for the administration and conservation of such cryofrozen cell batches.

So, faced with this veritable ‘basket of giant crabs’, and despite being a real dwarf compared to these two cold mastodons, we decided to act.

After many adventures and complexities, the details of which we will not go into here, we finally managed to extract more than 6,000 stem cell samples (mostly from families living in Switzerland, Germany and Austria) from the clutches of these giants and save them in our stem cell laboratory in Monthey.

This is important news because the many parents who have not been able to find their children's stem cells, or who do not wish to submit to the operational stranglehold imposed by FAMICORD-PBKM, will finally be able to turn to a long-established Swiss laboratory duly authorised for this purpose.

But first, in the face of the media frenzy that is once again brewing, we urge you:

Parents! Keep your faith in the future and consider storing your children's stem cells (*).

It's really worth it!

CORDSAVINGS IS A REPUTABLE SWISS STEM CELL LABORATORY, CLOSE TO PARENTS AND FULLY COMMITTED TO CHILDREN.

_________________

(*) what are stem cells?

Among the major challenges for medicine in the third millennium are clearly those of procreation, prediction and regeneration. While the first is already in the news (assisted reproduction, surrogate pregnancy or babies as pharmaceutical products), the others seem more distant, even though they are already so topical! In the field of regenerative medicine, stem cell research brings with it the hope of limiting ageing and repairing or replacing damaged cells or organs. To do this, it requires choices that are the subject of debate: the manipulation of embryos, the reprogramming of adult cells, or the storage of umbilical cord blood. In any case, society finds itself in a situation where it has to respond to high individual expectations, coupled with considerable scientific and economic issues, while the need for regulation and ethics is increasingly essential!

In the specific area of the conservation of umbilical cord blood at birth, Switzerland's position is unfortunately inconsistent. It provides very little encouragement and funding for public collection, and when it does, it does so very poorly, while it has to import the majority of the transplant units needed at exorbitant costs.

However, cord blood cells have exceptional therapeutic capacities for blood diseases, largely discovered and revealed in France by Professor Eliane Gluckman nearly 40 years ago. In allogeneic administration (with no link between donors and recipients), they have already saved tens of thousands of human lives, in children and adults, where they represent a more flexible alternative to bone marrow transplants. More recently, numerous clinical trials currently in progress tend to confirm that the cells of the umbilical cord itself also constitute a great hope for the treatment of certain degenerative pathologies such as diabetes and certain affections of the liver, kidney, heart or brain. These therapeutic possibilities, which are still being explored and validated, exist this time in allogeneic administration, but also autologous (the donation being directed to the child itself) and above all intrafamilial (where the chances of genetic compatibility allowing the success of the transplant are greatly increased within the same family). These possibilities therefore concern not only the treatment of blood diseases, but also many other organs.

List of curable diseases (in constant evolution) : https://cordsavings.com/en/stem-cells/list-of-curable-diseases

Diseases curable with stem cells (constantly evolving)

There are now more than 80 diseases that can be treated with hematopoietic stem cells (HSCs) collected from umbilical cord blood. For some diseases, these treatments are the only therapy, and for others, they are only used when first-line treatments have failed or the disease is very aggressive.

  • Allogeneic: The patient receives stem cells from a compatible donor, whether a sibling or unrelated donor.
  • Autologous: The patient receives his or her own stem cells. By registering cord blood in a family bank, parents ensure that their child can use his or her own cells for autologous treatment or that an immediate family member can benefit from related allogeneic treatment.

Cancers

Leukemias (a cancer of the blood immune system)

DiagnosisAutologousAllogeneic
Acute biphenotypic leukemianonoui
Acute lymphoblastic leukemia (ALL)nonoui
Acute myeloid leukemia (AML)nonoui
Acute undifferentiated leukemianonoui
Chronic lymphocytic leukemia (CLL)nonoui
Chronic myeloid leukemia (CML)nonoui
Juvenile chronic myeloid leukemia (JCML)nonoui
Juvenile myelomonocytic leukemia (JMML)nonoui

Myelodysplastic syndromes (also called pre-leukemias)

DiagnosisAutologousAllogeneic
Refractory anemianonoui
Refractory anemia with ringed sideroblastsnonoui
Refractory anemia with excess blastsnonoui
Refractory anemia with excess blasts in transformationnonoui
Chronic myelomonocytic leukemia (CMML)nonoui

Lymphomas (a cancer of the blood immune system)

DiagnosisAutologousAllogeneic
Hodgkin lymphomaouioui
Non-Hodgkin lymphoma (Burkitt lymphoma)ouioui

Solid tumors (not originating from blood or the immune system)

DiagnosisAutologousAllogeneic
Neuroblastomaouinon
Retinoblastomaouinon
Medulloblastomaouinon

Blood disorders

Anemias (deficiency or malformation of red blood cells)

DiagnosisAutologousAllogeneic
Aplastic anemianonoui
Congenital dyserythropoietic anemianonoui
Fanconi anemianonoui
Paroxysmal nocturnal hemoglobinuria (PNH)nonoui

Inherited red blood cell disorders

DiagnosisAutologousAllogeneic
Beta-thalassemia majornonoui
Diamond-Blackfan anemianonoui
Pure red cell aplasianonoui
Sickle cell diseasenonoui

Inherited platelet disorders

DiagnosisAutologousAllogeneic
Amégacaryocytose / Thrombocytopénie congénitalenonoui
Thrombasthénie de Glanzmannnonoui

Inherited immune system disorders: severe combined immunodeficiency (SCID)

DiagnosisAutologousAllogeneic
SCID with adenosine deaminase deficiency (ADA-SCID)nonoui
X-linked SCIDnonoui
SCID with absence of T and B cellsnonoui
SCID with absence of T cells and normal B cellsnonoui
Omenn syndromenonoui

Inherited immune system disorders: neutropenias

DiagnosisAutologousAllogeneic
Genetic infantile agranulocytosis (Kostmann syndrome)nonoui
Myelokathexisnonoui

Inherited immune system disorders – Others

DiagnosisAutologousAllogeneic
Ataxia-telangiectasianonoui
Nude lymphocyte syndromenonoui
Common variable immunodeficiencynonoui
DiGeorge syndromenonoui
Leukocyte adhesion deficiencynonoui
Lymphoproliferative disordersnonoui
X-linked lymphoproliferative disorder (also called Epstein-Barr virus susceptibility)nonoui
Wiskott-Aldrich syndromenonoui

Myeloproliferative disorders

DiagnosisAutologousAllogeneic
Acute myelofibrosisnonoui
Agnogenic myeloid metaplasia (myelofibrosis)nonoui
Polycythemia veranonoui
Essential thrombocythemianonoui

Phagocyte disorders

DiagnosisAutologousAllogeneic
Chediak-Higashi syndromenonoui
Chronic granulomatous diseasenonoui
Neutrophil actin deficiencynonoui
Reticular dysgenesisnonoui

Bone marrow cancers

DiagnosisAutologousAllogeneic
Multiple myelomaouioui
Primary plasma cell leukemia (PCL)ouioui
Secondary plasma cell leukemiaouioui
Waldenström macroglobulinemiaouioui

Immune disorders

Inherited diseases (immune system and other organs)

DiagnosisAutologousAllogeneic
Hypoplasia of cartilage and hairnonoui
Gunther's disease (erythropoietic porphyria)nonoui
Hermansky-Pudlak syndromenonoui
Pearson syndromenonoui
Shwachman-Diamond syndromenonoui
Systemic mastocytosisnonoui

Metabolic disorders

Mucopolysaccharidosis (MPS) storage diseases

DiagnosisAutologousAllogeneic
Hunter syndrome (MPS II)nonoui
Hurler syndrome (MPS IH)nonoui
Maroteaux-Lamy syndrome (MPS VI)nonoui
Morquio syndrome (MPS IV)nonoui
Sanfilippo syndrome (MPS III)nonoui
Scheie syndrome (MPS IS)nonoui

Sly syndrome, beta-glucuronidase deficiency (MPS VII)

DiagnosisAutologousAllogeneic
Mucolipidosis II (I-cell disease)nonoui

Leukodystrophy disorders

DiagnosisAutologousAllogeneic
Adrenoleukodystrophy (ALD) / Adrenomyeloneuropathy (AMN)nonoui
Krabbe disease (globoid cell leukodystrophy)nonoui
Metachromatic leukodystrophynonoui
Pelizaeus-Merzbacher diseasenonoui

Lysosomal storage diseases

DiagnosisAutologousAllogeneic
Niemann-Pick diseasenonoui
Sandhoff diseasenonoui
Wolman diseasenonoui

Inherited diseases - Others

DiagnosisAutologousAllogeneic
Lesch-Nyhan syndromenonoui
Osteopetrosisnonoui

 

Clinical trials using stem cells

Neonatal stem cells are at the center of hundreds of clinical trials across a variety of conditions, highlighting their versatility and therapeutic potential. In some cases, they are a primary treatment option, while in others, they are explored when conventional therapies prove insufficient. These ongoing trials highlight the immense potential and promise that neonatal stem cells hold to transform the medical treatment landscape and offer hope to patients facing a variety of health challenges.

Neurological disorders

DiagnosisCord bloodUmbilical tissuePlacental tissue
Alzheimer's diseaseokoknon
Autismokokok
Cerebral palsyokokok
Encephalopathyoknonnon
Developmental delayoknonnon
Hearing loss (acquired sensorineural)oknonnon
Intraventricular hemorrhageoknonnon
Parkinson's diseaseokokok
Spinal cord injuryokokok
Strokeokoknon
Traumatic brain injuryokokok

Autoimmune diseases

DiagnosisCord bloodUmbilical tissuePlacental tissue
Alopecia areataoknonnon
Amyotrophic lateral sclerosis (ALS)okoknon
Crohn's diseaseoknonnon
Eczema (atopic dermatitis)oknonnon
Graft-versus-host disease (GvHD)okokok
Lupusokoknon
Multiple sclerosisnonokok
Psoriasisnonoknon
Rheumatoid arthritisokoknon
Sclerodermaoknonnon
Systemic sclerosisoknonnon
Ulcerative colitisnonnonnon

Cardiovascular

DiagnosisCord bloodUmbilical tissuePlacental tissue
Acute myocardial infarction (heart attack)nonoknon
Cardiomyopathynonoknon
Critical limb ischemia (CLI)okoknon
Heart failurenonoknon
Peripheral artery disease (PAD)okoknon
Surgery for congenital heart defectsoknonnon

Diabetes

DiagnosisCord bloodUmbilical tissuePlacental tissue
Type 1 diabetes (autoimmune)oknonnon
Type 2 diabetesokoknon
Diabetic foot ulcernonoknon
Diabetic peripheral neuropathynonoknon

Genetic and/or metabolic disorders

DiagnosisCord bloodUmbilical tissuePlacental tissue
Frailty associated with agingokoknon
Duchenne muscular dystrophynonoknon
Epidermolysis bullosaoknonnon
Hereditary ataxianonoknon
Lysosomal storage diseasesoknonnon
Metabolic syndromenonoknon
Severe combined immunodeficiencyoknonnon
Spinal muscular atrophynonoknon
Tay-Sachs diseaseoknonnon

Orthopedic

DiagnosisCord bloodUmbilical tissuePlacental tissue
Ankylosing spondylitisnonoknon
Cartilage lesionokoknon
Cleft palate repairnonoknon
Non-union fracturesnonoknon
Osteoarthritisokoknon
Osteochondral lesionoknonnon
Spinal fusion surgerynonoknon

Others

DiagnosisCord bloodUmbilical tissuePlacental tissue
Acute respiratory distress syndrome (ARDS)nonoknon
Bronchopulmonary dysplasia (BPD)okoknon
Erectile dysfunctionnonoknon
Eye diseasesokokok
Fistulanonoknon
HIV (Human Immunodeficiency Virus)oknonnon
Liver cirrhosisokoknon
Liver failureokoknon
Peyronie's diseasenonoknon
Kidney failurenonoknon
Premature ovarian insufficiencyokoknon
Injuriesnonokok
Uterine scarsnonoknon

Frequently Asked Questions

On this page, you will find answers
to some of the most commonly
asked questions through our various
communication channels.

Feel free to contact us for any other
questions you may have.


Any doubts ? Contact us

  • Why Choose CordSavings?

    We are the only PRIVATE biobank in Switzerland, with quality guarantees (Swissmedic, OFSP, Allianz, etc.), and our laboratory is the ONLY one located in Switzerland (unlike our competitors) with the quality and seriousness that comes with it (protection of your data)!

    Made in Switzerland

    We owe NOTHING to potential shareholders

  • CordSavings and the Cryo-Save parents

    CordSavings has been entrusted with the custody of the only umbilical cord stem cell samples to have escaped the mess created by Cryo-Save, Famicord and CSG-BIO (*), following the bankruptcy of the former in September 2019, which itself followed the hasty and unauthorised departure of most of the samples - almost 300,000 children concerned worldwide - to the premises of PBKM (Famicord group) in Poland.

    Nearly 6,000 stem cell samples from families mainly from Switzerland, Germany, Austria and South Africa are actually stored at the CordSavings stem cell laboratory in Monthey, Switzerland.

    To the best of our knowledge, which is very limited given the legal disputes and criminal and civil proceedings between the three companies mentioned above (*) and their respective shareholders, CordSavings is at the disposal of the families affected by this Cryo-Save chaos for any further information and follow-up proposals.

    To contact us, please use exclusively this email address This email address is being protected from spambots. You need JavaScript enabled to view it. and indicate the CryoSave contract number(s) to facilitate our research.

  • What do "Stem Cells" mean?

    The cells and organs of the human body are made up of distinct cell types, but all cells originate from a common source: stem cells. These initial, undifferentiated cells can divide indefinitely and transform into any type of cell based on the biochemical signals they receive. They are distinguished by two characteristics: their ability to renew themselves and differentiate into specialized cells, such as those of the heart or pancreas.


    There are three types of stem cells: embryonic, embryonic germ, and adult.

  • How and when is umbilical cord blood collected?

    After birth, the gynecologist or midwife places two clamps on the umbilical cord and cuts between them, separating the baby from the mother. One clamp remains on the baby’s side, and the other on the placenta side.
    Then, a venous puncture is performed to collect the residual blood from the cord and placenta by gravity into a collection bag. This process is painless and safe for both the mother and the child.

  • If my baby is born by caesarean section, is it still possible to collect cord blood?

    The collection of umbilical cord blood can be performed during both vaginal deliveries and caesarean sections.

  • If I give birth prematurely, is it still possible to collect the blood?

    From the 34th week of pregnancy, collection can be considered. However, it will always be carried out only after evaluation by the practitioner, regardless of the situation.

  • What diseases can be treated with hematopoietic stem cell transfusions?

    Hematopoietic stem cell transplantation often represents the last chance for patients suffering from severe diseases of the hematopoietic system.


    Follow the link: List of over 80 treatable diseases.

  • Can I store cord tissue with CordSavings?

    CordSavings is authorized to store umbilical cord stem cells, which are widely used to regenerate neurons, joints, and bones.


    Perinatal stem cells have a regeneration capacity ten times greater than that of bone marrow. They are characterized by a lower immunological maturity, meaning that their transplantation results in fewer complications for the recipient.

  • My gynecologist is against the storage of cord blood; what can I do?

    Express your surprise.

    The Federal Office of Public Health (OFSP) informs that parents can store umbilical cord stem cells in a private bank for potential future needs.

    However, despite the evidence of the therapeutic benefits of stem cells and the promotion of cord blood collection, 70 to 80% of pregnant women lack knowledge on the subject and want to learn more. While 80 to 90% of women expect information from their healthcare professionals, only 15 to 30% receive it, and less than 50% of gynecologists feel sufficiently informed to answer their questions. This explains why women are often misinformed about the benefits, risks, and options for cord blood storage.

  • What happens if CordSavings goes out of business; what will happen to my stem cells?

    CordSavings has established a Business Continuity Plan to ensure the sustainability of stem cells, both biologically and financially.

    Additionally, each cryopreserved sample is insured up to CHF 8,000 with the Allianz Group.

  • Does umbilical cord blood collection affect the progress of labor?

    The collection of umbilical cord blood occurs only after the cord has been cut.
    The decision to cut the cord is made by the midwife or gynecologist, taking into account the circumstances of the delivery, the health of the mother and child, as well as the mother’s preferences.
    The collected blood does not affect the baby, as the procedure is performed at the most appropriate time by the healthcare professional.

  • Does umbilical cord blood collection prevent babies from benefiting from delayed cord clamping?

    The World Health Organization (WHO) recommends cutting the cord 1 to 3 minutes after birth to reduce infant anemia, allowing for the recovery of up to 80% of the remaining blood in the placenta.
    Delayed clamping improves iron status in babies. At CordSavings, only 10 ml of umbilical blood is needed to preserve stem cells, representing a fraction of the 200 ml available.
    CordSavings has developed an optimal extraction process to maximize the quality and potential use of stem cells.

SWISS BIOBANK

                    Switzerland - Suisse - Schweiz - Swizera

of stem cells
INDEPENDENT

Get in touch

Why save your baby's umbilical cord blood?

Umbilical cord blood is a valuable source of stem cells that can be used in the
treatment of a variety of conditions, such as leukemia and other blood disorders. These stem cells,
collected at birth from the umbilical cord, offer potential treatment options for
the child and, in some cases, for compatible family members.

cord blood

The difference with CordSavings...

We have always set the highest standards in our field by focusing on scientific innovation, quality customer service and absolute transparency. This allows us to offer a leading stem cell biobank in Switzerland, offering more personalized and humane solutions.

Umbilical Cord Blood

Umbilical Cord Blood

Preserve hematopoietic stem cells from your baby's cord blood, which are capable of producing all the cells of the blood and immune system. They have been used to treat over 80 diseases and are used in many clinical trials.

View service

Umbilical cord tissue

Umbilical cord tissue

Preserve cord tissue, which is a source of mesenchymal stem cells (MSCs) that can regenerate bone, cartilage, and muscle. Used in regenerative medicine, they are being studied in over 1,000 clinical trials to treat diseases such as cerebral palsy, arthritis, and type 1 diabetes.

View service

Placental tissue

Placental tissue

Preserving placental stem cells, which are promising in regenerative medicine and used to treat diseases such as multiple sclerosis and neurological disorders. Their use is growing, with more than 23,000 clinical trials and 40 approved therapies.

View service

"CordSavings is a family business with pure Swiss traditions"

The procedure to follow

How the collection process works

Understanding the process

CordSavings in the World

Our biobank enjoys international recognition and is considered one of the safest and most highly rated centers for cryopreservation and biological storage in the world. In fact, we regularly collaborate with several countries, including:

South AfricaSouth AfricaFrance* FranceLuxembourgLuxembourg
GermanyGermanyNetherlandsNetherlandsMonacoMonaco
AustriaAustriaHong KongHong KongPakistanPakistan
BahrainBahrainIndiaIndiaPolandPoland
BelgiumBelgiumIsraelIsraelPortugalPortugal
United Arab EmiratesUnited ArabItalyItalyRomaniaRomania
SpainSpainKenyaKenyaSlovakiaSlovakia
United StatesUnited StatesLatviaLatviaUkraineUkraine
BrazilBrazil    

* by derogation from the competent French authorities (Why ?)

Our partners

The Ark Monthey SuisseUnilabs Suissedhl expressSwissconnectparents guide to cord blood

CordSavings in the media

femmes et sports suisse

Cordsavings in newspaper

Link to the article

CordSavings, a Swiss family biobank, December 2022

Founded in 2012, CordSavings is pleased to have moved in 2022, still within the BioArk in Monthey, to brand new premises, designed and optimized by its team. It is with pleasure that the members of CordSavings welcome you today to their laboratory and their cryostorage areas (storage under nitrogen at -180°C). This new environment.

Founded in 2012, CordSavings is pleased to have moved in 2022, still within the BioArk in Monthey, to brand new premises, designed and optimized by its team. It is with pleasure that the members of CordSavings welcome you today to their laboratory and their cryostorage areas (storage under nitrogen at -180°C). This new environment even better reflects their perfectionism and their passion.

An umbilical cord blood bank launched in Valais

Umbilical cord blood can be used to treat cancers, including leukemia. But there is a serious lack of resources in Switzerland to collect and store it.

The CordSavings company in Monthey (VS) aims to solve this problem by creating a self-financed cord blood bank for everyone.

In Switzerland, parents who want to take advantage of the birth of their child to collect the stem cells contained in the umbilical cord have two options: either donate it to a public cord blood bank that makes it available to patients waiting for a transplant, or keep it for their own child by paying a private bank.

journal le matin cordsavings

Cordsavings in newspaper

link to the article

vaud famille

Cordsavings in newspaper

Link to the article

CORDSAVINGS: Life at the end of the Cord Tissue!

CORDSAVINGS, established in the BioArk Valaisans since 2012, is an active and recognized biobank in the cryopreservation of blood stem cells and umbilical cord tissue for therapeutic purposes.

Renowned cord blood banks and public healthcare institutions located within the European Union regularly call on CORDSAVINGS to process and preserve the tissue and cord blood of children in the most delicate situations (the latest cases transmitted being a case of lymphoma and a very serious genetic skin disease – Epidermolysis bullosa – according to a very elaborate protocol where both the cord blood and the preserved cord tissue will be used).

Within the local Swiss population, CORDSAVINGS is very appreciated and renowned for its human proximity and its constant attention to families. In keeping with its values ​​of solidarity, CORDSAVINGS actively participates in the collection of public cord blood with the Swiss association "Cordons pour Demain".

In addition to cord blood, at CORDSAVINGS you also have the possibility of storing stem cells from umbilical cord tissue.

Adresse

CORDSAVINGS SA
Route de l’Ile-au-Bois 1A
1870 Monthey (Switzerland)

Timetable

Monday – Friday: 08.00 – 17.00
On-call for births
and emergencies 7/7 - 24/24

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